pentobarbital will reduce the level or influence of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. No dosage adjustment for ondansetron is recommended for clients on these medicine.

Medicines that have restrictions other than prior authorization, amount restrictions, and stage therapy related to Every prescription.

pentobarbital will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Women must not pick out estradiol valerate/dienogest as their contraceptive though applying solid CYP3A4 inducers resulting from probable lessen in contraceptive efficacy.

pentobarbital will lower the extent or impact of phenytoin by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Monitor.

pentobarbital will reduce the level or effect of solifenacin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will lower the level or influence of methadone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.

Keep track of Intently (1)pentobarbital will lower the level or result of hydrocodone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Caution when discontinuing CYP3A4 inducers that are coadministered with hydrocodone; plasma concentrations of hydrocodone may possibly increase and may lead to possibly lethal respiratory depressionSerious - Use Option (one)hydrocodone, pentobarbital.

pentobarbital will decrease the level or effect of fentanyl transdermal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Coadministration of fentanyl with CYP3A4 inducers could lead to a decrease in fentanyl plasma concentrations, lack of efficacy or, possibly, development of the withdrawal syndrome inside of a client who's got designed Bodily dependence to fentanyl.

pentobarbital will lower the level or result of carbamazepine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

pentobarbital decreases outcomes of hemin by pharmacodynamic antagonism. Use Warning/Watch. Prescription drugs that increase delta-aminolevulinic acid synthetase might reduce hemin impact.

Cessation of click here benzodiazepines or other CNS depressants is desired typically. In some cases, monitoring at an increased volume of care for tapering CNS depressants can be correct. In Other individuals, little by little tapering a affected individual off of a prescribed benzodiazepine or other CNS depressant or lowering to the lowest successful dose may very well be suitable.

pentobarbital will reduce the level or outcome of ethinylestradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. The efficacy of hormonal contraceptives could possibly be lowered. Use of a nonhormonal contraceptive is recommended.

Using barbiturates as sedatives inside the postoperative surgical interval and as adjuncts to cancer chemotherapy is well recognized

pentobarbital will reduce the extent or impact of bosentan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unidentified.